Entity Details

Primary name SYNGAP1
Entity type gene
Source Source Link

Details

PrimaryID8831
RefseqGeneNG_016137
SymbolSYNGAP1
Namesynaptic Ras GTPase activating protein 1
Chromosome6
Location6p21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-12-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSYGP1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000165 MAPK cascade
GO:0005096 GTPase activator activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007265 Ras protein signal transduction
GO:0007389 pattern specification process
GO:0008542 visual learning
GO:0014069 postsynaptic density
GO:0016358 dendrite development
GO:0017124 SH3 domain binding
GO:0043113 receptor clustering
GO:0043198 dendritic shaft
GO:0043408 regulation of MAPK cascade
GO:0043524 negative regulation of neuron apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0046580 negative regulation of Ras protein signal transduction
GO:0048167 regulation of synaptic plasticity
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0050771 negative regulation of axonogenesis
GO:0050803 regulation of synapse structure or activity
GO:0098880 maintenance of postsynaptic specialization structure
GO:0098978 glutamatergic synapse

Diseases

Show/Hide Table

Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
SYNGAP1HSF2BPBioGRID, IntAct32296183 details
SYNGAP1MID2BioGRID, IntAct32296183 details
SYNGAP1SUOXBioGRID, IntAct32296183 details
SYNGAP1NCK2BioGRID, IntAct32296183 details
SYNGAP1TSSK3BioGRID, IntAct32296183 details
SYNGAP1TRIM27BioGRID, IntAct32296183 details
SYNGAP1NTAQ1BioGRID, IntAct32296183 details
SYNGAP1VENTXBioGRID, IntAct32296183 details
SYNGAP1TLX3BioGRID, IntAct32296183 details
SYNGAP1SPAG8BioGRID, IntAct32296183 details
SYNGAP1EFHC1BioGRID, IntAct32296183 details
SYNGAP1MKRN3BioGRID, IntAct32296183 details
SYNGAP1GUCD1BioGRID, IntAct32296183 details
SYNGAP1DLG4BioGRID, HPRD, MINT21653829 9581761 details
SYNGAP1ULK1BioGRID, HPRD15014045 details
SYNGAP1ULK2BioGRID, HPRD15014045 details
SYNGAP1DLG3BioGRID, HPRD9581761 details
SYNGAP1PDGFRBBioGRID, HPRD1374684 7678051 details
SYNGAP1OSTF1BioGRID32296183 details
SYNGAP1MGAT5BBioGRID32296183 details
SYNGAP1TRIP6HPRD11782456 details
SYNGAP1DLGAP4HPRD11487731 9581761 9620694 details
SYNGAP1OPTNIntAct20195357 details
SYNGAP1DISC1IntAct31413325 details
SYNGAP1LNX1BioGRID29121065 details
SYNGAP1LNX2BioGRID29121065 details
SYNGAP1GRIN2DHPRD10862698 details
SYNGAP1MPDZHPRD15312654 details
SYNGAP1GRIN1HPRD10862698 details
SYNGAP1KDRHPRD9405464 details
SYNGAP1GRIN2BHPRD9620694 details
SYNGAP1ESR2IntAct21182203 details
SYNGAP1YWHAGIntAct28514442 details
SYNGAP1H1-4BioGRID, IntAct30021884 details
SYNGAP1SART1BioGRID, IntAct30021884 details
SYNGAP1VIMBioGRID, IntAct30021884 details
SYNGAP1SAAL1BioGRID22939629 details
SYNGAP1RNF4BioGRID29180619 details
SYNGAP1PCNTBioGRID34079125 details
SYNGAP1HNRNPH1BioGRID26760575 details