Entity Details

Primary name ACVR1B
Entity type gene
Source Source Link

Details

PrimaryID91
RefseqGeneNG_022926
SymbolACVR1B
Nameactivin A receptor type 1B
Chromosome12
Location12q13.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsACV1B_HUMAN

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001701 in utero embryonic development
GO:0001942 hair follicle development
GO:0004674 protein serine/threonine kinase activity
GO:0004675 transmembrane receptor protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016361 activin receptor activity, type I
GO:0018107 peptidyl-threonine phosphorylation
GO:0030308 negative regulation of cell growth
GO:0031625 ubiquitin protein ligase binding
GO:0032924 activin receptor signaling pathway
GO:0032927 positive regulation of activin receptor signaling pathway
GO:0034711 inhibin binding
GO:0038092 nodal signaling pathway
GO:0043235 receptor complex
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0046545 development of primary female sexual characteristics
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048179 activin receptor complex
GO:0048185 activin binding
GO:0071363 cellular response to growth factor stimulus
GO:0097191 extrinsic apoptotic signaling pathway
GO:1901165 positive regulation of trophoblast cell migration

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
ACVR1BPRKACBBioGRID, IntAct21988832 details
ACVR1BOS9BioGRID, IntAct21988832 details
ACVR1BRXRABioGRID, IntAct21988832 details
ACVR1BBAG6BioGRID, IntAct21988832 details
ACVR1BFKBP1Abhf-ucl, BioGRID15908921 16720724 details
ACVR1BBMPR2BioGRID7791754 details
ACVR1BTDGF1BioGRID, HPRD11909953 28126904 details
ACVR1BNEDD4LBioGRID19953087 details
ACVR1BBAMBIBioGRID19758997 details
ACVR1BOTUB1BioGRID25872870 details
ACVR1BNODALBioGRID28126904 details
ACVR1BHSP90AB1IntAct22939624 details
ACVR1BSMAD7bhf-ucl, BioGRID, HPRD12023024 16720724 20663871 details
ACVR1BACVR2BBioGRID, HPRD8612709 8622651 details
ACVR1BINHBBBioGRID, HPRD11266516 12032389 15196700 9202237 details
ACVR1BINHBABioGRID, HPRD8397373 9202237 details
ACVR1BSMAD2BioGRID, HPRD9892009 details
ACVR1BSMAD3BioGRID9892009 details
ACVR1BACVR2ABioGRID11927552 8612709 9892009 details
ACVR1BACVR1BioGRID26186194 8612709 details
ACVR1BSNX2BioGRID, HPRD11279102 details
ACVR1BSNX1BioGRID, HPRD11279102 details
ACVR1BSMURF1BioGRID12857866 16720724 details
ACVR1BTSC22D1BioGRID21791611 details
ACVR1BIGSF1BioGRID, HPRD11266516 details
ACVR1BSMAD6BioGRID20663871 details
ACVR1BHSP90AA1BioGRID22939624 details
ACVR1BPEG10BioGRID15611116 details
ACVR1BSMAD4HPRD9892009 details
ACVR1BINHBCHPRD12651901 details
ACVR1BACVR1BHPRD15196700 details
ACVR1BTGFBRAP1HPRD11278302 details
ACVR1BXIAPBioGRID, IntAct25241761 details
ACVR1BTSNAXBioGRID, IntAct26496610 details
ACVR1BVPS16BioGRID, IntAct26496610 details
ACVR1BZNF644BioGRID, IntAct26496610 details
ACVR1BTMEM30BBioGRID, IntAct28514442 details
ACVR1BADGRG5BioGRID, IntAct28514442 details
ACVR1BMRAP2BioGRID, IntAct28514442 details
ACVR1BSPINT2BioGRID26186194 details
ACVR1BTSPAN3BioGRID26186194 details
ACVR1BTGFBR2BioGRID26186194 details
ACVR1BTMEM30ABioGRID26186194 details
ACVR1BTSPAN17BioGRID26186194 details
ACVR1BHEPACAM2BioGRID26186194 details
ACVR1BNTRK1BioGRID25921289 details
ACVR1BHAVCR1BioGRID29742433 details
ACVR1BRNF123BioGRID29676528 details
ACVR1BELAVL1BioGRID19322201 details