Entity Details

Primary name CD28
Entity type gene
Source Source Link

Details

PrimaryID940
RefseqGeneNG_029618
SymbolCD28
NameCD28 molecule
Chromosome2
Location2q33.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-06-10
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCD28_HUMAN

GO terms

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GOName
GO:0001772 immunological synapse
GO:0001819 positive regulation of cytokine production
GO:0002020 protease binding
GO:0002863 positive regulation of inflammatory response to antigenic stimulus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006959 humoral immune response
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015026 coreceptor activity
GO:0019901 protein kinase binding
GO:0031295 T cell costimulation
GO:0032733 positive regulation of interleukin-10 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032753 positive regulation of interleukin-4 production
GO:0042102 positive regulation of T cell proliferation
GO:0042110 T cell activation
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0045060 negative thymic T cell selection
GO:0045066 regulatory T cell differentiation
GO:0045070 positive regulation of viral genome replication
GO:0045589 regulation of regulatory T cell differentiation
GO:0045727 positive regulation of translation
GO:0045840 positive regulation of mitotic nuclear division
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0048304 positive regulation of isotype switching to IgG isotypes
GO:0050690 regulation of defense response to virus by virus
GO:0050852 T cell receptor signaling pathway
GO:0051897 positive regulation of protein kinase B signaling
GO:0097190 apoptotic signaling pathway
GO:0098636 protein complex involved in cell adhesion

Diseases

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