Entity Details
| Primary name |
ALAT2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q8TD30 |
| EntryName | ALAT2_HUMAN |
| FullName | Alanine aminotransferase 2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 523 |
| SequenceStatus | complete |
| DateCreated | 2006-07-25 |
| DateModified | 2021-06-02 |
Subcellular Location
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Domains
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| Domain | Name | Category | Type |
| IPR004839 | Aminotransferase, class I/classII | Domain | Domain |
| IPR015421 | Pyridoxal phosphate-dependent transferase, major domain | Family | Homologous superfamily |
| IPR015422 | Pyridoxal phosphate-dependent transferase, small domain | Family | Homologous superfamily |
| IPR015424 | Pyridoxal phosphate-dependent transferase | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 616281 | OMIM | Mental retardation, autosomal recessive 49 (MRT49) | A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRT49 patients show a developmental encephalopathy characterized by rapid onset of failure to thrive and microcephaly, as well as profoundly delayed development. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00114 | Pyridoxal phosphate | Drugbank | small molecule |
| DB00142 | Glutamic acid | Drugbank | small molecule |
| DB00160 | Alanine | Drugbank | small molecule |
| DB00780 | Phenelzine | Drugbank | small molecule |
Interactions
2 interactions