Entity Details

Primary name TF3B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92994
EntryNameTF3B_HUMAN
FullNameTranscription factor IIIB 90 kDa subunit
TaxID9606
Evidenceevidence at protein level
Length677
SequenceStatuscomplete
DateCreated2002-05-02
DateModified2021-06-02

Ontological Relatives

GenesBRF1

GO terms

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GOName
GO:0000126 transcription factor TFIIIB complex
GO:0000995 RNA polymerase III general transcription initiation factor activity
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006352 DNA-templated transcription, initiation
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation from RNA polymerase III promoter
GO:0009303 rRNA transcription
GO:0009304 tRNA transcription
GO:0017025 TBP-class protein binding
GO:0045945 positive regulation of transcription by RNA polymerase III
GO:0046872 metal ion binding
GO:0070897 transcription preinitiation complex assembly
GO:0097550 transcription preinitiation complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000812 Transcription factor TFIIBFamilyFamily
IPR011665 Brf1, TBP-binding domainDomainDomain
IPR013137 Zinc finger, TFIIB-typeDomainDomain
IPR013150 Transcription factor TFIIB, cyclin-like domainDomainDomain
IPR013763 Cyclin-likeDomainDomain
IPR029529 Transcription factor IIIB subunit Brf1FamilyFamily
IPR036915 Cyclin-like superfamilyFamilyHomologous superfamily

Diseases

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