Entity Details

Primary name HEPH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BQS7
EntryNameHEPH_HUMAN
FullNameHephaestin
TaxID9606
Evidenceevidence at protein level
Length1158
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-04-07

Ontological Relatives

GenesHEPH

GO terms

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GOName
GO:0004322 ferroxidase activity
GO:0005507 copper ion binding
GO:0005886 plasma membrane
GO:0006825 copper ion transport
GO:0006826 iron ion transport
GO:0006879 cellular iron ion homeostasis
GO:0008198 ferrous iron binding
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016491 oxidoreductase activity
GO:0048471 perinuclear region of cytoplasm
GO:0055072 iron ion homeostasis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002355 Multicopper oxidase, copper-binding siteSiteBinding site
IPR008972 CupredoxinFamilyHomologous superfamily
IPR011706 Multicopper oxidase, C-terminalDomainDomain
IPR011707 Multicopper oxidase, N-termianlDomainDomain
IPR027154 HephaestinFamilyFamily
IPR033138 Multicopper oxidases, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB09130 CopperDrugbanksmall molecule
DB13257 Ferrous sulfate anhydrousDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HEPH_HUMANGLRX3_HUMANIntAct32296183 details