Entity Details

Primary name CAC1I_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9P0X4
EntryNameCAC1I_HUMAN
FullNameVoltage-dependent T-type calcium channel subunit alpha-1I
TaxID9606
Evidenceevidence at protein level
Length2223
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesCACNA1I

GO terms

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GOName
GO:0001518 voltage-gated sodium channel complex
GO:0005245 voltage-gated calcium channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005891 voltage-gated calcium channel complex
GO:0007165 signal transduction
GO:0008332 low voltage-gated calcium channel activity
GO:0019228 neuronal action potential
GO:0030317 flagellated sperm motility
GO:0030431 sleep
GO:0034765 regulation of ion transmembrane transport
GO:0043005 neuron projection
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0070509 calcium ion import
GO:0086010 membrane depolarization during action potential

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002077 Voltage-dependent calcium channel, alpha-1 subunitFamilyFamily
IPR005445 Voltage-dependent calcium channel, T-type, alpha-1 subunitFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR030162 Voltage-dependent calcium channel, T-type, alpha-1I subunitFamilyFamily
IPR043203 Voltage-gated cation channel calcium and sodiumFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00153 ErgocalciferolDrugbanksmall molecule
DB00228 EnfluraneDrugbanksmall molecule
DB00381 AmlodipineDrugbanksmall molecule
DB00421 SpironolactoneDrugbanksmall molecule
DB00568 CinnarizineDrugbanksmall molecule
DB00617 ParamethadioneDrugbanksmall molecule
DB00909 ZonisamideDrugbanksmall molecule
DB01115 NifedipineDrugbanksmall molecule
DB01118 AmiodaroneDrugbanksmall molecule
DB01388 MibefradilDrugbanksmall molecule
DB04841 FlunarizineDrugbanksmall molecule
DB06152 NylidrinDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB09089 TrimebutineDrugbanksmall molecule
DB09231 BenidipineDrugbanksmall molecule
DB09235 EfonidipineDrugbanksmall molecule
DB09238 ManidipineDrugbanksmall molecule
DB09498 Strontium chloride Sr-89Swissprotsmall molecule
DB11093 Calcium citrateDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB13746 BioallethrinDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CAC1I_HUMANCTSR1_HUMANIntAct16740636 details
CAC1I_HUMANCTSR2_HUMANIntAct16740636 details