Entity Details

Primary name HECD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9ULT8
EntryNameHECD1_HUMAN
FullNameE3 ubiquitin-protein ligase HECTD1
TaxID9606
Evidenceevidence at protein level
Length2610
SequenceStatuscomplete
DateCreated2003-02-12
DateModified2021-06-02

Ontological Relatives

GenesHECTD1

GO terms

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GOName
GO:0003170 heart valve development
GO:0003281 ventricular septum development
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035904 aorta development
GO:0046872 metal ion binding
GO:0048856 anatomical structure development
GO:0061630 ubiquitin protein ligase activity
GO:0070534 protein K63-linked ubiquitination

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000569 HECT domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR010606 Mib-herc2DomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR012919 SUN domainDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037252 Mib/herc2 domain superfamilyFamilyHomologous superfamily
IPR041200 FKBP3, basic tilted helix bundle domainDomainDomain

Diseases

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