Entity Details

Primary name FCER2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06734
EntryNameFCER2_HUMAN
FullNameLow affinity immunoglobulin epsilon Fc receptor
TaxID9606
Evidenceevidence at protein level
Length321
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesFCER2

GO terms

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GOName
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0005178 integrin binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007219 Notch signaling pathway
GO:0009897 external side of plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019863 IgE binding
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
GO:0051000 positive regulation of nitric-oxide synthase activity
GO:0051712 positive regulation of killing of cells of other organism
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR001304 C-type lectin-likeDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR018378 C-type lectin, conserved siteSiteConserved site
IPR033989 CD209-like, C-type lectin-like domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB06162 LumiliximabDrugbankbiotech