Entity Details

Primary name SAP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17900
EntryNameSAP3_HUMAN
FullNameGanglioside GM2 activator
TaxID9606
Evidenceevidence at protein level
Length193
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesGM2A

GO terms

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GOName
GO:0005319 lipid transporter activity
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0006687 glycosphingolipid metabolic process
GO:0006689 ganglioside catabolic process
GO:0006869 lipid transport
GO:0007611 learning or memory
GO:0009313 oligosaccharide catabolic process
GO:0009898 cytoplasmic side of plasma membrane
GO:0016004 phospholipase activator activity
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019915 lipid storage
GO:0032428 beta-N-acetylgalactosaminidase activity
GO:0035578 azurophil granule lumen
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0050885 neuromuscular process controlling balance
GO:0051345 positive regulation of hydrolase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR003172 MD-2-related lipid-recognition domainDomainDomain
IPR028996 Ganglioside GM2 activatorFamilyFamily
IPR036846 GM2-AP, lipid-recognition domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02261 Platelet Activating FactorDrugbanksmall molecule
DB03017 Lauric acidDrugbanksmall molecule
DB03633 Lpc-EtherDrugbanksmall molecule
DB04660 Choline alfoscerateDrugbanksmall molecule
DB08231 Myristic acidDrugbanksmall molecule

Interactions

4 interactions