Entity Details

Primary name MX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP20592
EntryNameMX2_HUMAN
FullNameInterferon-induced GTP-binding protein Mx2
TaxID9606
Evidenceevidence at protein level
Length715
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesMX2

GO terms

Show/Hide Table
GOName
GO:0000266 mitochondrial fission
GO:0003374 dynamin family protein polymerization involved in mitochondrial fission
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006952 defense response
GO:0008017 microtubule binding
GO:0009615 response to virus
GO:0014069 postsynaptic density
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane
GO:0030424 axon
GO:0031410 cytoplasmic vesicle
GO:0031623 receptor internalization
GO:0031966 mitochondrial membrane
GO:0035455 response to interferon-alpha
GO:0044327 dendritic spine head
GO:0046822 regulation of nucleocytoplasmic transport
GO:0050803 regulation of synapse structure or activity
GO:0051028 mRNA transport
GO:0051607 defense response to virus
GO:0051726 regulation of cell cycle
GO:0060337 type I interferon signaling pathway
GO:0061025 membrane fusion
GO:0098793 presynapse
GO:0098844 postsynaptic endocytic zone membrane
GO:0098884 postsynaptic neurotransmitter receptor internalization

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000375 Dynamin stalk domainDomainDomain
IPR001401 Dynamin, GTPase domainDomainDomain
IPR003130 Dynamin GTPase effectorDomainDomain
IPR019762 Dynamin, GTPase region, conserved siteSiteConserved site
IPR020850 GTPase effector domainDomainDomain
IPR022812 DynaminFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030381 Dynamin-type guanine nucleotide-binding (G) domainDomainDomain

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
MX2_HUMANPIAS2_HUMANBioGRID, IntAct25416956 details
MX2_HUMANATRIP_HUMANBioGRID, IntAct25416956 details
MX2_HUMANEHMT2_HUMANBioGRID, IntAct25416956 32296183 details
MX2_HUMANMX2_HUMANBioGRID, HPRD9405443 details