Entity Details
| Primary name |
THAS_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P24557 |
| EntryName | THAS_HUMAN |
| FullName | Thromboxane-A synthase |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 533 |
| SequenceStatus | complete |
| DateCreated | 1992-03-01 |
| DateModified | 2021-06-02 |
Subcellular Location
Show/Hide Table
| Subcellular Location |
| Endoplasmic reticulum membrane |
Domains
Show/Hide Table
| Domain | Name | Category | Type |
| IPR001128 | Cytochrome P450 | Family | Family |
| IPR002401 | Cytochrome P450, E-class, group I | Family | Family |
| IPR017972 | Cytochrome P450, conserved site | Site | Conserved site |
| IPR036396 | Cytochrome P450 superfamily | Family | Homologous superfamily |
Diseases
Show/Hide Table
| Disease ID | Source | Name | Description |
| 231095 | OMIM | Ghosal hematodiaphyseal dysplasia (GHDD) | Rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
Show/Hide Table
| Drug | Name | Source | Type |
| DB00795 | Sulfasalazine | Drugbank | small molecule |
| DB01207 | Ridogrel | Drugbank | small molecule |
| DB03052 | Dazoxiben | Drugbank | small molecule |
| DB05505 | NM-702 | Drugbank | small molecule |
Interactions
1 interaction