Entity Details

Primary name ILEU_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30740
EntryNameILEU_HUMAN
FullNameLeukocyte elastase inhibitor
TaxID9606
Evidenceevidence at protein level
Length379
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesSERPINB1

GO terms

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GOName
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0010951 negative regulation of endopeptidase activity
GO:0016020 membrane
GO:0030414 peptidase inhibitor activity
GO:0032691 negative regulation of interleukin-1 beta production
GO:0034774 secretory granule lumen
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043312 neutrophil degranulation
GO:0044342 type B pancreatic cell proliferation
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytolytic granule
Cytoplasm
Early endosome
Secreted

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR015557 Leukocyte elastase inhibitor (serpin B1)FamilyFamily
IPR023795 Serpin, conserved siteSiteConserved site
IPR023796 Serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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Interactions

4 interactions