Entity Details

Primary name CASP5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51878
EntryNameCASP5_HUMAN
FullNameCaspase-5
TaxID9606
Evidenceevidence at protein level
Length434
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCASP5

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005737 cytoplasm
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0008234 cysteine-type peptidase activity
GO:0021762 substantia nigra development
GO:0042981 regulation of apoptotic process
GO:0050727 regulation of inflammatory response
GO:0071260 cellular response to mechanical stimulus
GO:0072558 NLRP1 inflammasome complex
GO:0097194 execution phase of apoptosis
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001309 Peptidase C14, p20 domainDomainDomain
IPR001315 CARD domainDomainDomain
IPR002138 Peptidase C14, caspase non-catalytic subunit p10DomainDomain
IPR002398 Peptidase C14 familyFamilyFamily
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR015917 Peptidase C14A, caspase catalytic domainDomainDomain
IPR016129 Peptidase family C14A, His active siteSiteActive site
IPR029030 Caspase-like domain superfamilyFamilyHomologous superfamily
IPR033139 Peptidase family C14A, cysteine active siteSiteActive site

Diseases

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Interactions

4 interactions