Entity Details

Primary name FGF8
Entity type gene
Source Source Link

Details

PrimaryID2253
RefseqGeneNG_007151
SymbolFGF8
Namefibroblast growth factor 8
Chromosome10
Location10q24.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsFGF8_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001656 metanephros development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001759 organ induction
GO:0001823 mesonephros development
GO:0001839 neural plate morphogenesis
GO:0001934 positive regulation of protein phosphorylation
GO:0001947 heart looping
GO:0001974 blood vessel remodeling
GO:0003007 heart morphogenesis
GO:0003148 outflow tract septum morphogenesis
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0005104 fibroblast growth factor receptor binding
GO:0005105 type 1 fibroblast growth factor receptor binding
GO:0005111 type 2 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006979 response to oxidative stress
GO:0007369 gastrulation
GO:0008045 motor neuron axon guidance
GO:0008078 mesodermal cell migration
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008406 gonad development
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009653 anatomical structure morphogenesis
GO:0009887 animal organ morphogenesis
GO:0009897 external side of plasma membrane
GO:0009953 dorsal/ventral pattern formation
GO:0010628 positive regulation of gene expression
GO:0014070 response to organic cyclic compound
GO:0021543 pallium development
GO:0021544 subpallium development
GO:0021798 forebrain dorsal/ventral pattern formation
GO:0021846 cell proliferation in forebrain
GO:0021884 forebrain neuron development
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030334 regulation of cell migration
GO:0030539 male genitalia development
GO:0030878 thyroid gland development
GO:0030916 otic vesicle formation
GO:0030917 midbrain-hindbrain boundary development
GO:0033563 dorsal/ventral axon guidance
GO:0035050 embryonic heart tube development
GO:0035108 limb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0035909 aorta morphogenesis
GO:0042056 chemoattractant activity
GO:0042476 odontogenesis
GO:0042487 regulation of odontogenesis of dentin-containing tooth
GO:0042493 response to drug
GO:0043524 negative regulation of neuron apoptotic process
GO:0045165 cell fate commitment
GO:0045597 positive regulation of cell differentiation
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0045840 positive regulation of mitotic nuclear division
GO:0046622 positive regulation of organ growth
GO:0048702 embryonic neurocranium morphogenesis
GO:0048853 forebrain morphogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0055026 negative regulation of cardiac muscle tissue development
GO:0060037 pharyngeal system development
GO:0060128 corticotropin hormone secreting cell differentiation
GO:0060129 thyroid-stimulating hormone-secreting cell differentiation
GO:0060348 bone development
GO:0060425 lung morphogenesis
GO:0060445 branching involved in salivary gland morphogenesis
GO:0060563 neuroepithelial cell differentiation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071542 dopaminergic neuron differentiation
GO:0090134 cell migration involved in mesendoderm migration
GO:0120223 larynx morphogenesis

Diseases

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Interactions

102 interactions

InteractorPartnerSourcesPublicationsLink
FGF8FGFR2BioGRID, IntAct18199118 25241761 details
FGF8FGFR1BioGRID, DIP, HPRD, IntAct10574949 18199118 22244757 25241761 details
FGF8FGFR3BioGRID, DIP, HPRD10574949 22244757 details
FGF8PTX3BioGRID25912421 details
FGF8FGFR4HPRD10736564 details
FGF8H2AXBioGRID, IntAct28514442 details
FGF8IFT88BioGRID, IntAct28514442 details
FGF8MYBBP1ABioGRID, IntAct28514442 details
FGF8IFT74BioGRID, IntAct28514442 details
FGF8IFT81BioGRID, IntAct28514442 details
FGF8ANKHD1-EIF4EBP3BioGRID, IntAct28514442 details
FGF8ANKHD1BioGRID, IntAct28514442 details
FGF8DHX30BioGRID, IntAct28514442 details
FGF8KRR1BioGRID, IntAct28514442 details
FGF8DDX10BioGRID, IntAct28514442 details
FGF8CEBPZBioGRID, IntAct28514442 details
FGF8MRPS9BioGRID, IntAct28514442 details
FGF8MRPS35BioGRID, IntAct28514442 details
FGF8PRR3BioGRID, IntAct28514442 details
FGF8RPS15BioGRID, IntAct28514442 details
FGF8RPS16BioGRID, IntAct28514442 details
FGF8RPS3ABioGRID, IntAct28514442 details
FGF8DAP3BioGRID, IntAct28514442 details
FGF8RBMS1BioGRID, IntAct28514442 details
FGF8RPS3BioGRID, IntAct28514442 details
FGF8H1-6BioGRID, IntAct28514442 details
FGF8CDK11BBioGRID, IntAct28514442 details
FGF8NSA2BioGRID, IntAct28514442 details
FGF8ANKRD17BioGRID, IntAct28514442 details
FGF8DKC1BioGRID, IntAct28514442 details
FGF8URB1BioGRID, IntAct28514442 details
FGF8RRP8BioGRID, IntAct28514442 details
FGF8NVLBioGRID, IntAct28514442 details
FGF8MPHOSPH10BioGRID, IntAct28514442 details
FGF8AP3B1BioGRID, IntAct28514442 details
FGF8RBM19BioGRID, IntAct28514442 details
FGF8NOC2LBioGRID, IntAct28514442 details
FGF8IFT52BioGRID, IntAct28514442 details
FGF8WDR3BioGRID, IntAct28514442 details
FGF8RPL26L1BioGRID, IntAct28514442 details
FGF8VANGL2BioGRID, IntAct28514442 details
FGF8IFT172BioGRID, IntAct28514442 details
FGF8DAXXBioGRID, IntAct28514442 details
FGF8IFT80BioGRID, IntAct28514442 details
FGF8CDK12BioGRID, IntAct28514442 details
FGF8DDX56BioGRID, IntAct28514442 details
FGF8AATFBioGRID, IntAct28514442 details
FGF8IFT57BioGRID, IntAct28514442 details
FGF8SDAD1BioGRID, IntAct28514442 details
FGF8DDX18BioGRID, IntAct28514442 details
FGF8DDX21BioGRID, IntAct28514442 details
FGF8PPANIntAct28514442 details
FGF8PPAN-P2RY11BioGRID, IntAct28514442 details
FGF8MRPL40BioGRID, IntAct28514442 details
FGF8MRPS30BioGRID, IntAct28514442 details
FGF8CWC22BioGRID, IntAct28514442 details
FGF8MOV10BioGRID, IntAct28514442 details
FGF8C17orf75BioGRID, IntAct28514442 details
FGF8DDX31BioGRID, IntAct28514442 details
FGF8YTHDC2BioGRID, IntAct28514442 details
FGF8DHX36BioGRID, IntAct28514442 details
FGF8NAT10BioGRID, IntAct28514442 details
FGF8DDX24BioGRID, IntAct28514442 details
FGF8REXO4BioGRID, IntAct28514442 details
FGF8WDR11BioGRID, IntAct28514442 details
FGF8GTPBP4BioGRID, IntAct28514442 details
FGF8STRBPBioGRID, IntAct28514442 details
FGF8SRPK1BioGRID, IntAct28514442 details
FGF8ZFRBioGRID, IntAct28514442 details
FGF8PTCD3BioGRID, IntAct28514442 details
FGF8NSUN4BioGRID, IntAct28514442 details
FGF8C18orf25BioGRID, IntAct28514442 details
FGF8UPF1BioGRID, IntAct28514442 details
FGF8NOC3LBioGRID, IntAct28514442 details
FGF8BRIX1BioGRID, IntAct28514442 details
FGF8DDX54BioGRID, IntAct28514442 details
FGF8ZCRB1BioGRID, IntAct28514442 details
FGF8VANGL1BioGRID, IntAct28514442 details
FGF8WDR36BioGRID, IntAct28514442 details
FGF8DDX55BioGRID, IntAct28514442 details
FGF8NOA1BioGRID, IntAct28514442 details
FGF8DDX51BioGRID, IntAct28514442 details
FGF8ZC3H8BioGRID, IntAct28514442 details
FGF8XRN1BioGRID, IntAct28514442 details
FGF8CHERPBioGRID, IntAct28514442 details
FGF8TTC30ABioGRID, IntAct28514442 details
FGF8MRPL52BioGRID, IntAct28514442 details
FGF8MRPL10BioGRID, IntAct28514442 details
FGF8TRMT1LBioGRID, IntAct28514442 details
FGF8NOL8BioGRID, IntAct28514442 details
FGF8NKAPD1BioGRID, IntAct28514442 details
FGF8LARP1BioGRID, IntAct28514442 details
FGF8DHX57BioGRID, IntAct28514442 details
FGF8FAM91A1BioGRID, IntAct28514442 details
FGF8RRP12BioGRID, IntAct28514442 details
FGF8GLYR1BioGRID, IntAct28514442 details
FGF8TRIM71BioGRID, IntAct28514442 details
FGF8PUM3BioGRID, IntAct28514442 details
FGF8PWP2BioGRID, IntAct28514442 details
FGF8BMS1BioGRID, IntAct28514442 details
FGF8PDCD11BioGRID, IntAct28514442 details
FGF8RELAIntAct16683270 details