Entity Details

Primary name PSME4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14997
EntryNamePSME4_HUMAN
FullNameProteasome activator complex subunit 4
TaxID9606
Evidenceevidence at protein level
Length1843
SequenceStatuscomplete
DateCreated2007-03-20
DateModified2021-06-02

Ontological Relatives

GenesPSME4

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000209 protein polyubiquitination
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006521 regulation of cellular amino acid metabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007275 multicellular organism development
GO:0010499 proteasomal ubiquitin-independent protein catabolic process
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0016504 peptidase activator activity
GO:0016579 protein deubiquitination
GO:0016607 nuclear speck
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035093 spermatogenesis, exchange of chromosomal proteins
GO:0036388 pre-replicative complex assembly
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043488 regulation of mRNA stability
GO:0043687 post-translational protein modification
GO:0050852 T cell receptor signaling pathway
GO:0055085 transmembrane transport
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070577 lysine-acetylated histone binding
GO:0070628 proteasome binding
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1990111 spermatoproteasome complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR021843 Proteasome activator complex subunit 4 C-terminal domainDomainDomain
IPR032430 Proteasome activator Blm10, mid regionDomainDomain
IPR035309 Proteasome activator complex subunit 4FamilyFamily

Diseases

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