Entity Details

Primary name HPGD
Entity type gene
Source Source Link

Details

PrimaryID3248
RefseqGeneNG_011689
SymbolHPGD
Name15-hydroxyprostaglandin dehydrogenase
Chromosome4
Location4q34.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-10-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPGDH_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001822 kidney development
GO:0004957 prostaglandin E receptor activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006693 prostaglandin metabolic process
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007565 female pregnancy
GO:0007567 parturition
GO:0016323 basolateral plasma membrane
GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019372 lipoxygenase pathway
GO:0030728 ovulation
GO:0032355 response to estradiol
GO:0032496 response to lipopolysaccharide
GO:0042759 long-chain fatty acid biosynthetic process
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0045471 response to ethanol
GO:0045786 negative regulation of cell cycle
GO:0051287 NAD binding
GO:0070062 extracellular exosome
GO:0070403 NAD+ binding
GO:0070493 thrombin-activated receptor signaling pathway
GO:0097070 ductus arteriosus closure
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1905828 regulation of prostaglandin catabolic process
GO:2001301 lipoxin biosynthetic process

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HPGDAPPBioGRID21832049 details
HPGDNR2C2BioGRID30463901 details