Entity Details

Primary name SLURP1
Entity type gene
Source Source Link

Details

PrimaryID57152
RefseqGeneNG_011494
SymbolSLURP1
Namesecreted LY6/PLAUR domain containing 1
Chromosome8
Location8q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSLUR1_HUMAN

GO terms

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GOName
GO:0001775 cell activation
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007155 cell adhesion
GO:0007626 locomotory behavior
GO:0008285 negative regulation of cell population proliferation
GO:0010839 negative regulation of keratinocyte proliferation
GO:0030336 negative regulation of cell migration
GO:0030549 acetylcholine receptor activator activity
GO:0038195 urokinase plasminogen activator signaling pathway
GO:0050884 neuromuscular process controlling posture
GO:0070062 extracellular exosome

Diseases

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Disease IDSourceNameDescription
248300 OMIMMal de Meleda (MDM)A rare autosomal recessive skin disorder, characterized by diffuse transgressive palmoplantar keratoderma with keratotic lesions extending onto the dorsa of the hands and the feet (transgrediens). Patients may have hyperhidrosis. Other features include perioral erythema, lichenoid plaques on the knees and the elbows, and nail abnormalities. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
SLURP1PLAUUniProt25168896 details
SLURP1CHRNA7UniProt26905431 details
SLURP1CHRFAM7AUniProt26905431 details
SLURP1ASXL2BioGRID, IntAct27705803 details