Entity Details

Primary name RUBIC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92622
EntryNameRUBIC_HUMAN
FullNameRun domain Beclin-1-interacting and cysteine-rich domain-containing protein
TaxID9606
Evidenceevidence at protein level
Length972
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesRUBCN

GO terms

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GOName
GO:0002376 immune system process
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005829 cytosol
GO:0006897 endocytosis
GO:0006909 phagocytosis
GO:0006914 autophagy
GO:0010507 negative regulation of autophagy
GO:0043231 intracellular membrane-bounded organelle
GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity
GO:0045806 negative regulation of endocytosis
GO:0071985 multivesicular body sorting pathway
GO:1901097 negative regulation of autophagosome maturation
GO:1901981 phosphatidylinositol phosphate binding

Subcellular Location

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Subcellular Location
Early endosome
Late endosome
Lysosome

Domains

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DomainNameCategoryType
IPR004012 RUN domainDomainDomain
IPR025258 Putative zinc-RING and/or ribbonDomainDomain
IPR037213 RUN domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
RUBIC_HUMANUVRAG_HUMANBioGRID, IntAct, UniProt19270696 20562859 21062745 22493499 25533187 30686098 details
RUBIC_HUMANPK3C3_HUMANBioGRID, IntAct, UniProt19270696 20562859 21062745 24980960 25533187 30686098 details
RUBIC_HUMANREQU_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANNDK7_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANDRC4_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANFAM9B_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANTEANC_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANBRD1_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANENKD1_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANF161A_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANZN648_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANZN250_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANBYST_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANVEZF1_HUMANBioGRID, IntAct32296183 details
RUBIC_HUMANEXOC1_HUMANBioGRID21241894 details
RUBIC_HUMANANR11_HUMANBioGRID32296183 details
RUBIC_HUMANSMAD9_HUMANHPRD15231748 details
RUBIC_HUMANBECN1_HUMANBioGRID, IntAct, UniProt19270693 19270696 19372752 20562859 21062745 22493499 23954414 24034250 24980960 25594178 25891078 26496610 26876213 27621469 29587298 31373534 31696776 details
RUBIC_HUMANEGFR_HUMANBioGRID, IntAct24034250 25594178 29587298 details
RUBIC_HUMANPI3R4_HUMANBioGRID, UniProt19270696 21062745 details
RUBIC_HUMAN1433E_HUMANBioGRID19608861 details
RUBIC_HUMANEXOC8_HUMANBioGRID21241894 details
RUBIC_HUMANEXOC2_HUMANBioGRID21241894 details
RUBIC_HUMANNEMO_HUMANBioGRID28392573 details
RUBIC_HUMANMTOR_HUMANBioGRID25533187 details
RUBIC_HUMANBAKOR_HUMANBioGRID19270693 details