Entity Details

Primary name NTNG2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96CW9
EntryNameNTNG2_HUMAN
FullNameNetrin-G2
TaxID9606
Evidenceevidence at protein level
Length530
SequenceStatuscomplete
DateCreated2003-09-19
DateModified2021-06-02

Ontological Relatives

GenesNTNG2

GO terms

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GOName
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007409 axonogenesis
GO:0009887 animal organ morphogenesis
GO:0009888 tissue development
GO:0010975 regulation of neuron projection development
GO:0016477 cell migration
GO:0030424 axon
GO:0034446 substrate adhesion-dependent cell spreading
GO:0043256 laminin complex
GO:0045171 intercellular bridge
GO:0046658 anchored component of plasma membrane
GO:0050804 modulation of chemical synaptic transmission
GO:0070831 basement membrane assembly
GO:0090543 Flemming body
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098698 postsynaptic specialization assembly
GO:0098978 glutamatergic synapse
GO:0099029 anchored component of presynaptic active zone membrane
GO:0099560 synaptic membrane adhesion
GO:0150011 regulation of neuron projection arborization
GO:1905606 regulation of presynapse assembly
GO:2001222 regulation of neuron migration

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR002049 Laminin EGF domainDomainDomain
IPR008211 Laminin, N-terminalDomainDomain

Diseases

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Disease IDSourceNameDescription
618718 OMIMNeurodevelopmental disorder with behavioral abnormalities, absent speech, and hypotonia (NEDBASH)An autosomal recessive disorder characterized by global developmental delay with severely impaired intellectual development, impaired motor development, axial and peripheral hypotonia, poor speech and significant behavioral abnormalities, including autism spectrum disorder, hyperactivity, mood disorders, aggression, hand and face stereotypies, sleep disturbances, anxiety, self-injurious behavior, and bruxism. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions