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Entity Details
Primary name
PIWL1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q96J94
EntryName
PIWL1_HUMAN
FullName
Piwi-like protein 1
TaxID
9606
Evidence
evidence at protein level
Length
861
SequenceStatus
complete
DateCreated
2006-05-16
DateModified
2021-06-02
Ontological Relatives
Genes
PIWIL1
GO terms
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GO
Name
GO:0003727
single-stranded RNA binding
GO:0003729
mRNA binding
GO:0004521
endoribonuclease activity
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0006417
regulation of translation
GO:0007275
multicellular organism development
GO:0007283
spermatogenesis
GO:0007286
spermatid development
GO:0010529
negative regulation of transposition
GO:0019901
protein kinase binding
GO:0031047
gene silencing by RNA
GO:0033391
chromatoid body
GO:0034584
piRNA binding
GO:0034587
piRNA metabolic process
GO:0035093
spermatogenesis, exchange of chromosomal proteins
GO:0043186
P granule
GO:0046872
metal ion binding
GO:0051321
meiotic cell cycle
GO:0097433
dense body
GO:0140262
mRNA cap binding complex binding
GO:1905538
polysome binding
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR003100
PAZ domain
Domain
Domain
IPR003165
Piwi domain
Domain
Domain
IPR012337
Ribonuclease H-like superfamily
Family
Homologous superfamily
IPR014811
Argonaute, linker 1 domain
Domain
Domain
IPR031320
GAGE
Domain
Domain
IPR031326
Piwi-like protein 1
Family
Family
IPR036085
PAZ domain superfamily
Family
Homologous superfamily
IPR036397
Ribonuclease H superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
19 interactions
Interactor
Partner
Sources
Publications
Link
PIWL1_HUMAN
DICER_HUMAN
BioGRID, HPRD, UniProt
14749716
details
PIWL1_HUMAN
SND1_HUMAN
DIP
20937909
details
PIWL1_HUMAN
TDRKH_HUMAN
BioGRID, DIP, MINT
20937909
24981860
details
PIWL1_HUMAN
TRI54_HUMAN
BioGRID, IntAct
31391242
details
PIWL1_HUMAN
DYN2_HUMAN
IntAct
32814053
details
PIWL1_HUMAN
JPH3_HUMAN
IntAct
32814053
details
PIWL1_HUMAN
HD_HUMAN
IntAct
32814053
details
PIWL1_HUMAN
ATX1_HUMAN
IntAct
32814053
details
PIWL1_HUMAN
STMN1_HUMAN
BioGRID
26317901
details
PIWL1_HUMAN
FKBP5_HUMAN
IntAct
25036637
details
PIWL1_HUMAN
HSF2_HUMAN
IntAct
25036637
details
PIWL1_HUMAN
NUDC_HUMAN
IntAct
25036637
details
PIWL1_HUMAN
NUDC3_HUMAN
IntAct
25036637
details
PIWL1_HUMAN
HS90A_HUMAN
IntAct
25036637
details
PIWL1_HUMAN
CYBP_HUMAN
IntAct
25036637
details
PIWL1_HUMAN
TEBP_HUMAN
IntAct
25036637
details
PIWL1_HUMAN
TBA1B_HUMAN
BioGRID
26317901
details
PIWL1_HUMAN
TBB3_HUMAN
BioGRID
26317901
details
PIWL1_HUMAN
RNF8_HUMAN
BioGRID
28552346
details
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