Entity Details

Primary name IL17F_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PD4
EntryNameIL17F_HUMAN
FullNameInterleukin-17F
TaxID9606
Evidenceevidence at protein level
Length163
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesIL17F

GO terms

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GOName
GO:0001819 positive regulation of cytokine production
GO:0002225 positive regulation of antimicrobial peptide production
GO:0002250 adaptive immune response
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0016525 negative regulation of angiogenesis
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production
GO:0032663 regulation of interleukin-2 production
GO:0032675 regulation of interleukin-6 production
GO:0032677 regulation of interleukin-8 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032761 positive regulation of lymphotoxin A production
GO:0042803 protein homodimerization activity
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0051216 cartilage development
GO:0097400 interleukin-17-mediated signaling pathway
GO:1900017 positive regulation of cytokine production involved in inflammatory response
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR010345 Interleukin-17 familyFamilyFamily
IPR020440 Interleukin-17, chordataFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
613956 OMIMCandidiasis, familial, 6 (CANDF6)A primary immunodeficiency disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. The disease is caused by variants affecting the gene represented in this entry.

Interactions

3 interactions