Entity Details

Primary name AGRA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PE1
EntryNameAGRA2_HUMAN
FullNameAdhesion G protein-coupled receptor A2
TaxID9606
Evidenceevidence at protein level
Length1338
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesADGRA2

GO terms

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GOName
GO:0002040 sprouting angiogenesis
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007417 central nervous system development
GO:0009986 cell surface
GO:0010595 positive regulation of endothelial cell migration
GO:0016021 integral component of membrane
GO:0016055 Wnt signaling pathway
GO:0030175 filopodium
GO:0043542 endothelial cell migration
GO:0045765 regulation of angiogenesis
GO:0050920 regulation of chemotaxis
GO:0090210 regulation of establishment of blood-brain barrier
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:1990909 Wnt signalosome

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000203 GPS motifDomainDomain
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001611 Leucine-rich repeatRepeatRepeat
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AGRA2_HUMANDLG1_HUMANBioGRID, IntAct, MINT15021905 24550280 details
AGRA2_HUMANCCDB1_HUMANBioGRID, IntAct32296183 details