Entity Details

Primary name CHAC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BUX1
EntryNameCHAC1_HUMAN
FullNameGlutathione-specific gamma-glutamylcyclotransferase 1
TaxID9606
Evidenceevidence at protein level
Length222
SequenceStatuscomplete
DateCreated2006-05-30
DateModified2021-06-02

Ontological Relatives

GenesCHAC1

GO terms

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GOName
GO:0003839 gamma-glutamylcyclotransferase activity
GO:0005112 Notch binding
GO:0005737 cytoplasm
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0006750 glutathione biosynthetic process
GO:0006751 glutathione catabolic process
GO:0006986 response to unfolded protein
GO:0007219 Notch signaling pathway
GO:0010955 negative regulation of protein processing
GO:0022008 neurogenesis
GO:0045746 negative regulation of Notch signaling pathway
GO:0061928 glutathione specific gamma-glutamylcyclotransferase activity
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Subcellular Location

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Subcellular Location
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR006840 Glutathione-specific gamma-glutamylcyclotransferaseFamilyFamily
IPR013024 Gamma-glutamyl cyclotransferase-likeDomainDomain
IPR036568 Gamma-glutamyl cyclotransferase-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CHAC1_HUMANRHXF2_HUMANBioGRID, HPRD, IntAct16189514 details