Entity Details

Primary name ITPA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BY32
EntryNameITPA_HUMAN
FullNameInosine triphosphate pyrophosphatase
TaxID9606
Evidenceevidence at protein level
Length194
SequenceStatuscomplete
DateCreated2003-04-23
DateModified2021-06-02

Ontological Relatives

GenesITPA

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006193 ITP catabolic process
GO:0006195 purine nucleotide catabolic process
GO:0009143 nucleoside triphosphate catabolic process
GO:0009204 deoxyribonucleoside triphosphate catabolic process
GO:0035529 NADH pyrophosphatase activity
GO:0035870 dITP diphosphatase activity
GO:0036218 dTTP diphosphatase activity
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0046872 metal ion binding
GO:0047429 nucleoside-triphosphate diphosphatase activity
GO:0051276 chromosome organization

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002637 Ham1-like proteinFamilyFamily
IPR027502 Inosine triphosphate pyrophosphataseFamilyFamily
IPR029001 Inosine triphosphate pyrophosphatase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00993 AzathioprineDrugbanksmall molecule
DB04272 Citric acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ITPA_HUMANITPA_HUMANBioGRID, IntAct25416956 32296183 details