Entity Details

Primary name HESX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBX0
EntryNameHESX1_HUMAN
FullNameHomeobox expressed in ES cells 1
TaxID9606
Evidenceevidence at protein level
Length185
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesHESX1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007420 brain development
GO:0008022 protein C-terminus binding
GO:0008406 gonad development
GO:0010467 gene expression
GO:0019827 stem cell population maintenance
GO:0021983 pituitary gland development
GO:0030878 thyroid gland development
GO:0030916 otic vesicle formation
GO:0035264 multicellular organism growth
GO:0042803 protein homodimerization activity
GO:0043010 camera-type eye development
GO:0043584 nose development
GO:0045995 regulation of embryonic development
GO:0047485 protein N-terminus binding
GO:0048853 forebrain morphogenesis
GO:0048861 leukemia inhibitory factor signaling pathway
GO:0048863 stem cell differentiation
GO:0060070 canonical Wnt signaling pathway
GO:0070371 ERK1 and ERK2 cascade
GO:0071276 cellular response to cadmium ion
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR043402 Homeobox expressed in ES cells 1FamilyFamily

Diseases

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