Entity Details

Primary name ASAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9ULH1
EntryNameASAP1_HUMAN
FullNameArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length1129
SequenceStatuscomplete
DateCreated2003-09-26
DateModified2021-06-02

Ontological Relatives

GenesASAP1

GO terms

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GOName
GO:0001786 phosphatidylserine binding
GO:0002102 podosome
GO:0005096 GTPase activator activity
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005829 cytosol
GO:0031253 cell projection membrane
GO:0043197 dendritic spine
GO:0045296 cadherin binding
GO:0046872 metal ion binding
GO:0060271 cilium assembly
GO:0061000 negative regulation of dendritic spine development
GO:0071803 positive regulation of podosome assembly
GO:1903527 positive regulation of membrane tubulation

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR001164 Arf GTPase activating proteinDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR037844 ASAP, PH domainDomainDomain
IPR037928 ASAP1, BAR domainDomainDomain
IPR038016 ASAP1, SH3 domainDomainDomain
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily
IPR043593 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing proteinFamilyFamily

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
ASAP1_HUMANHCK_HUMANHPRD, MINT12029088 16636290 details
ASAP1_HUMANSH3K1_HUMANBioGRID, HPRD, IntAct, MINT15090612 15719014 17255943 19531213 28514442 31980649 details
ASAP1_HUMANSRC8_HUMANBioGRID, MINT12672817 15719014 16636290 17255943 17893324 details
ASAP1_HUMANPLCG1_HUMANIntAct17474147 details
ASAP1_HUMANABL1_HUMANIntAct17474147 details
ASAP1_HUMANCRK_HUMANBioGRID, IntAct17474147 19380743 31980649 9819391 details
ASAP1_HUMANSRC_HUMANBioGRID, HPRD, IntAct, MINT16636290 17474147 9819391 details
ASAP1_HUMANFYN_HUMANIntAct, MINT16636290 17474147 details
ASAP1_HUMANGRB2_HUMANBioGRID, IntAct17474147 19380743 20936779 21706016 21988832 28514442 31980649 details
ASAP1_HUMANNCK1_HUMANIntAct, MINT16636290 17474147 details
ASAP1_HUMANP85A_HUMANIntAct17474147 details
ASAP1_HUMANPAXI_HUMANBioGRID, HPRD, MINT12149250 15632162 16636290 details
ASAP1_HUMANTEC_HUMANMINT16636290 details
ASAP1_HUMANPPIP1_HUMANMINT16636290 details
ASAP1_HUMANPACN2_HUMANBioGRID, MINT16636290 19041431 details
ASAP1_HUMANNPHP1_HUMANMINT16636290 details
ASAP1_HUMANGRAP2_HUMANMINT16636290 details
ASAP1_HUMANDLG1_HUMANMINT16636290 details
ASAP1_HUMANSH3G2_HUMANMINT16636290 details
ASAP1_HUMANSTAM1_HUMANMINT16636290 details
ASAP1_HUMANSNX9_HUMANMINT16636290 details
ASAP1_HUMANAPC_HUMANBioGRID, MINT18786926 20509626 details
ASAP1_HUMANDNJB6_HUMANBioGRID, IntAct23414517 details
ASAP1_HUMANPACN3_HUMANBioGRID, HPRD15719014 19041431 details
ASAP1_HUMANARF6_HUMANBioGRID16527809 18094045 details
ASAP1_HUMANRFIP3_HUMANBioGRID18685082 details
ASAP1_HUMANARF1_HUMANBioGRID, HPRD16223492 16332543 details
ASAP1_HUMANREPS2_HUMANHPRD12149250 details
ASAP1_HUMANFAK2_HUMANHPRD12771146 details
ASAP1_HUMANCBLB_HUMANBioGRID, MINT17255943 details
ASAP1_HUMANUBC_HUMANMINT17255943 details
ASAP1_HUMANCBL_HUMANBioGRID, HPRD, MINT17255943 details
ASAP1_HUMANCD2AP_HUMANBioGRID, IntAct15632162 31413325 details
ASAP1_HUMANEXOC1_HUMANIntAct31413325 details
ASAP1_HUMANPACN1_HUMANBioGRID19041431 details
ASAP1_HUMANCIP4_HUMANBioGRID19041431 details
ASAP1_HUMANFCSD1_HUMANBioGRID19041431 details
ASAP1_HUMANARAP3_HUMANBioGRID15090612 details
ASAP1_HUMANFAK1_HUMANBioGRID15632162 17893324 18786926 34079125 details
ASAP1_HUMANLRRK1_HUMANBioGRID20697350 details
ASAP1_HUMANRFIP1_HUMANBioGRID18685082 details
ASAP1_HUMANRFIP2_HUMANBioGRID18685082 details
ASAP1_HUMANARHG2_HUMANBioGRID21352810 details