Entity Details

Primary name DHPR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09417
EntryNameDHPR_HUMAN
FullNameDihydropteridine reductase
TaxID9606
Evidenceevidence at protein level
Length244
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesQDPR

GO terms

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GOName
GO:0001889 liver development
GO:0004155 6,7-dihydropteridine reductase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006520 cellular amino acid metabolic process
GO:0006558 L-phenylalanine metabolic process
GO:0006559 L-phenylalanine catabolic process
GO:0006729 tetrahydrobiopterin biosynthetic process
GO:0009055 electron transfer activity
GO:0010044 response to aluminum ion
GO:0010288 response to lead ion
GO:0033762 response to glucagon
GO:0035690 cellular response to drug
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0051066 dihydrobiopterin metabolic process
GO:0070062 extracellular exosome
GO:0070402 NADPH binding
GO:0070404 NADH binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB03814 2-(N-morpholino)ethanesulfonic acidDrugbanksmall molecule

Interactions

6 interactions