Entity Details

Primary name T2EA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29083
EntryNameT2EA_HUMAN
FullNameGeneral transcription factor IIE subunit 1
TaxID9606
Evidenceevidence at protein level
Length439
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesGTF2E1

GO terms

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GOName
GO:0001113 transcription open complex formation at RNA polymerase II promoter
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005669 transcription factor TFIID complex
GO:0005673 transcription factor TFIIE complex
GO:0005829 cytosol
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0016032 viral process
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0042795 snRNA transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0097550 transcription preinitiation complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002853 Transcription initiation factor IIE subunit alpha, N-terminalDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013137 Zinc finger, TFIIB-typeDomainDomain
IPR017919 Transcription factor TFE/TFIIEalpha HTH domainDomainDomain
IPR021600 Transcription factor TFIIE alpha subunit, C-terminalDomainDomain
IPR024550 TFIIEalpha/SarR/Rpc3 HTH domainDomainDomain
IPR039997 Transcription factor EFamilyFamily

Diseases

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Interactions

38 interactions

InteractorPartnerSourcesPublicationsLink
T2EA_HUMANT2EB_HUMANBioGRID, HPRD, IntAct, MINT11113176 12665589 16547462 17643375 22939629 25492609 26344197 28514442 32296183 7926747 9677423 details
T2EA_HUMANTF2H1_HUMANBioGRID, DIP, HPRD, IntAct, MINT11113176 18160537 18354501 25492609 32296183 details
T2EA_HUMANSRPK2_HUMANBioGRID, IntAct23602568 details
T2EA_HUMANNRARP_HUMANBioGRID, IntAct32296183 details
T2EA_HUMANTBC21_HUMANBioGRID, IntAct32296183 details
T2EA_HUMANERCC2_HUMANBioGRID, DIP25492609 27193682 details
T2EA_HUMANCDK7_HUMANBioGRID, IntAct15282296 23064645 25492609 29568061 details
T2EA_HUMANZBTB9_HUMANBioGRID, IntAct20211142 details
T2EA_HUMANTRI29_HUMANBioGRID, IntAct20211142 details
T2EA_HUMANZSCA1_HUMANBioGRID, IntAct20211142 details
T2EA_HUMANPHS2_HUMANBioGRID, IntAct20211142 details
T2EA_HUMANNEMO_HUMANBioGRID, IntAct20211142 details
T2EA_HUMANTRI15_HUMANBioGRID, IntAct20211142 details
T2EA_HUMANMTG8R_HUMANBioGRID, IntAct20211142 details
T2EA_HUMANTF2B_HUMANBioGRID, HPRD11113176 25492609 9159119 details
T2EA_HUMANTBP_HUMANBioGRID, HPRD11113176 25492609 7926747 9159119 details
T2EA_HUMANTAF11_HUMANBioGRID9159119 details
T2EA_HUMANRPB1_HUMANBioGRID7926747 9159119 details
T2EA_HUMANT2FA_HUMANBioGRID25492609 7926747 9121429 9159119 details
T2EA_HUMANTF2H4_HUMANBioGRID, HPRD11113176 9159119 details
T2EA_HUMANTAF6_HUMANBioGRID, HPRD7667268 7926747 details
T2EA_HUMANTF2AA_HUMANBioGRID, HPRD11509574 details
T2EA_HUMANSND1_HUMANBioGRID, HPRD7651391 details
T2EA_HUMANTLE5_HUMANBioGRID, HPRD11416139 details
T2EA_HUMANT2FB_HUMANBioGRID, HPRD11113176 25492609 7926747 details
T2EA_HUMANTAF1_HUMANBioGRID7926747 details
T2EA_HUMANERCC3_HUMANBioGRID, HPRD25492609 7926747 8152490 details
T2EA_HUMANTCEA1_HUMANBioGRID, HPRD10454562 9305922 details
T2EA_HUMANTIF1A_HUMANBioGRID, HPRD9632676 details
T2EA_HUMANA4_HUMANBioGRID21832049 details
T2EA_HUMANTF2H2_HUMANBioGRID25492609 details
T2EA_HUMANTF2H3_HUMANBioGRID25492609 details
T2EA_HUMANTF2H5_HUMANBioGRID25492609 details
T2EA_HUMANOGT1_HUMANBioGRID32994395 details
T2EA_HUMANBRCA1_HUMANBioGRID9159119 details
T2EA_HUMANMED21_HUMANBioGRID9159119 details
T2EA_HUMANMCAF1_HUMANBioGRID19106100 26344197 details
T2EA_HUMANT2AG_HUMANHPRD11509574 details