Entity Details

Primary name TSPO_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30536
EntryNameTSPO_HUMAN
FullNameTranslocator protein
TaxID9606
Evidenceevidence at protein level
Length169
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesTSPO

GO terms

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GOName
GO:0005497 androgen binding
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006626 protein targeting to mitochondrion
GO:0006700 C21-steroid hormone biosynthetic process
GO:0006783 heme biosynthetic process
GO:0006820 anion transport
GO:0006821 chloride transport
GO:0006869 lipid transport
GO:0007568 aging
GO:0008202 steroid metabolic process
GO:0008347 glial cell migration
GO:0008503 benzodiazepine receptor activity
GO:0010042 response to manganese ion
GO:0010266 response to vitamin B1
GO:0010940 positive regulation of necrotic cell death
GO:0014012 peripheral nervous system axon regeneration
GO:0015485 cholesterol binding
GO:0016021 integral component of membrane
GO:0030325 adrenal gland development
GO:0031397 negative regulation of protein ubiquitination
GO:0032374 regulation of cholesterol transport
GO:0032570 response to progesterone
GO:0032720 negative regulation of tumor necrosis factor production
GO:0033574 response to testosterone
GO:0042127 regulation of cell population proliferation
GO:0042493 response to drug
GO:0043065 positive regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0044325 transmembrane transporter binding
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0048266 behavioral response to pain
GO:0050810 regulation of steroid biosynthetic process
GO:0051901 positive regulation of mitochondrial depolarization
GO:0051928 positive regulation of calcium ion transport
GO:0060242 contact inhibition
GO:0060252 positive regulation of glial cell proliferation
GO:0060253 negative regulation of glial cell proliferation
GO:0070062 extracellular exosome
GO:0071222 cellular response to lipopolysaccharide
GO:0071294 cellular response to zinc ion
GO:0071476 cellular hypotonic response
GO:0072656 maintenance of protein location in mitochondrion
GO:1903147 negative regulation of autophagy of mitochondrion
GO:1903579 negative regulation of ATP metabolic process
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Mitochondrion membrane

Domains

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DomainNameCategoryType
IPR004307 TspO/MBR-related proteinFamilyFamily
IPR030164 Translocator proteinFamilyFamily
IPR038330 TspO/MBR-related superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01178 ChlormezanoneDrugbanksmall molecule
DB01198 ZopicloneDrugbanksmall molecule