Entity Details

Primary name SL9A3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48764
EntryNameSL9A3_HUMAN
FullNameSodium/hydrogen exchanger 3
TaxID9606
Evidenceevidence at protein level
Length834
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesSLC9A3

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005903 brush border
GO:0006811 ion transport
GO:0009986 cell surface
GO:0015385 sodium:proton antiporter activity
GO:0015386 potassium:proton antiporter activity
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030165 PDZ domain binding
GO:0031526 brush border membrane
GO:0051453 regulation of intracellular pH
GO:0070062 extracellular exosome
GO:0071805 potassium ion transmembrane transport
GO:0098719 sodium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Apical cell membrane

Domains

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DomainNameCategoryType
IPR004709 Na+/H+ exchangerFamilyFamily
IPR006153 Cation/H+ exchangerDomainDomain
IPR018410 Na+/H+ exchanger, isoforms 3/5FamilyFamily
IPR018422 Cation/H+ exchanger, CPA1 familyFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB11761 TenapanorDrugbanksmall molecule