Entity Details

Primary name SCOT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55809
EntryNameSCOT1_HUMAN
FullNameSuccinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length520
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesOXCT1

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0007420 brain development
GO:0007507 heart development
GO:0007584 response to nutrient
GO:0008260 3-oxoacid CoA-transferase activity
GO:0008410 CoA-transferase activity
GO:0009725 response to hormone
GO:0014823 response to activity
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042182 ketone catabolic process
GO:0042493 response to drug
GO:0042594 response to starvation
GO:0042802 identical protein binding
GO:0045471 response to ethanol
GO:0046950 cellular ketone body metabolic process
GO:0046952 ketone body catabolic process
GO:0060612 adipose tissue development

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR004163 Coenzyme A transferase binding siteSiteBinding site
IPR004164 Coenzyme A transferase active siteSiteActive site
IPR004165 Coenzyme A transferase family IFamilyFamily
IPR012791 3-oxoacid CoA-transferase, subunit BDomainDomain
IPR012792 3-oxoacid CoA-transferase, subunit ADomainDomain
IPR014388 3-oxoacid CoA-transferaseFamilyFamily
IPR037171 NagB/RpiA transferase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00139 Succinic acidDrugbanksmall molecule
DB02731 Ethylmercurithiosalicylic acidDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SCOT1_HUMANPSN1_HUMANBioGRID, IntAct21163940 details
SCOT1_HUMANOGT1_HUMANBioGRID32994395 details
SCOT1_HUMANTFCP2_HUMANIntAct20195357 details