Entity Details

Primary name RGF1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ0VAM2
EntryNameRGF1B_HUMAN
FullNameRas-GEF domain-containing family member 1B
TaxID9606
Evidenceevidence at protein level
Length473
SequenceStatuscomplete
DateCreated2007-08-21
DateModified2021-06-02

Ontological Relatives

GenesRASGEF1B

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005769 early endosome
GO:0005770 late endosome
GO:0007264 small GTPase mediated signal transduction
GO:0030496 midbody

Subcellular Location

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Subcellular Location
Early endosome
Late endosome
Midbody

Domains

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DomainNameCategoryType
IPR000651 Ras-like guanine nucleotide exchange factor, N-terminalDomainDomain
IPR001895 Ras guanine-nucleotide exchange factors catalytic domainDomainDomain
IPR008937 Ras-like guanine nucleotide exchange factorFamilyFamily
IPR019804 Ras guanine-nucleotide exchange factor, conserved siteSiteConserved site
IPR023578 Ras guanine nucleotide exchange factor domain superfamilyFamilyHomologous superfamily
IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
RGF1B_HUMANPDLI7_HUMANBioGRID, IntAct32296183 details
RGF1B_HUMANT10IP_HUMANBioGRID, IntAct32296183 details
RGF1B_HUMANPKHF2_HUMANBioGRID, IntAct32296183 details
RGF1B_HUMANBAZ2B_HUMANBioGRID32296183 details