Entity Details

Primary name FZD5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13467
EntryNameFZD5_HUMAN
FullNameFrizzled-5
TaxID9606
Evidenceevidence at protein level
Length585
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFZD5

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000578 embryonic axis specification
GO:0001525 angiogenesis
GO:0001540 amyloid-beta binding
GO:0002726 positive regulation of T cell cytokine production
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005923 bicellular tight junction
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0007416 synapse assembly
GO:0008285 negative regulation of cell population proliferation
GO:0008289 lipid binding
GO:0008595 anterior/posterior axis specification, embryo
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0017147 Wnt-protein binding
GO:0019901 protein kinase binding
GO:0030182 neuron differentiation
GO:0030424 axon
GO:0030425 dendrite
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0031077 post-embryonic camera-type eye development
GO:0031625 ubiquitin protein ligase binding
GO:0031901 early endosome membrane
GO:0032729 positive regulation of interferon-gamma production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0033077 T cell differentiation in thymus
GO:0042813 Wnt-activated receptor activity
GO:0043204 perikaryon
GO:0043507 positive regulation of JUN kinase activity
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048469 cell maturation
GO:0048471 perinuclear region of cytoplasm
GO:0048596 embryonic camera-type eye morphogenesis
GO:0060061 Spemann organizer formation
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060561 apoptotic process involved in morphogenesis
GO:0060670 branching involved in labyrinthine layer morphogenesis
GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development
GO:0060716 labyrinthine layer blood vessel development
GO:0060718 chorionic trophoblast cell differentiation
GO:0071219 cellular response to molecule of bacterial origin
GO:1901382 regulation of chorionic trophoblast cell proliferation
GO:1903146 regulation of autophagy of mitochondrion
GO:1903955 positive regulation of protein targeting to mitochondrion
GO:1904886 beta-catenin destruction complex disassembly
GO:2000810 regulation of bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Golgi apparatus membrane
Perikaryon

Domains

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DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR037441 Frizzled-5, CRD domainDomainDomain

Diseases

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