Entity Details

Primary name HOMER2
Entity type gene
Source Source Link

Details

PrimaryID9455
RefseqGeneNG_029435
SymbolHOMER2
Namehomer scaffold protein 2
Chromosome15
Location15q25.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-04-14
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHOME2_HUMAN

GO terms

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GOName
GO:0003779 actin binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007216 G protein-coupled glutamate receptor signaling pathway
GO:0007605 sensory perception of sound
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0014069 postsynaptic density
GO:0019904 protein domain specific binding
GO:0030160 synaptic receptor adaptor activity
GO:0030425 dendrite
GO:0032426 stereocilium tip
GO:0032703 negative regulation of interleukin-2 production
GO:0035256 G protein-coupled glutamate receptor binding
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043229 intracellular organelle
GO:0044877 protein-containing complex binding
GO:0045177 apical part of cell
GO:0048148 behavioral response to cocaine
GO:0048875 chemical homeostasis within a tissue
GO:0070885 negative regulation of calcineurin-NFAT signaling cascade
GO:0098978 glutamatergic synapse
GO:2001256 regulation of store-operated calcium entry

Diseases

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Disease IDSourceNameDescription
616707 OMIMDeafness, autosomal dominant, 68 (DFNA68)A form of non-syndromic sensorineural hearing loss with postlingual onset. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. The disease is caused by variants affecting the gene represented in this entry.