Entity Details

Primary name ASTL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6HA08
EntryNameASTL_HUMAN
FullNameAstacin-like metalloendopeptidase
TaxID9606
Evidenceevidence at protein level
Length431
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesASTL

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007155 cell adhesion
GO:0008270 zinc ion binding
GO:0009566 fertilization
GO:0010954 positive regulation of protein processing
GO:0030133 transport vesicle
GO:0060468 prevention of polyspermy
GO:0060473 cortical granule
GO:0070001 aspartic-type peptidase activity
GO:0070002 glutamic-type peptidase activity
GO:2000360 negative regulation of binding of sperm to zona pellucida

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR001506 Peptidase M12ADomainDomain
IPR006026 Peptidase, metallopeptidaseDomainDomain
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ASTL_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details