Entity Details

Primary name ULK3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6PHR2
EntryNameULK3_HUMAN
FullNameSerine/threonine-protein kinase ULK3
TaxID9606
Evidenceevidence at protein level
Length472
SequenceStatuscomplete
DateCreated2006-09-19
DateModified2021-06-02

Ontological Relatives

GenesULK3

GO terms

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GOName
GO:0000407 phagophore assembly site
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006914 autophagy
GO:0007224 smoothened signaling pathway
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045880 positive regulation of smoothened signaling pathway
GO:0046777 protein autophosphorylation
GO:0072537 fibroblast activation
GO:0090398 cellular senescence
GO:0097542 ciliary tip
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR007330 MIT domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036181 MIT domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ULK3_HUMANCDC37_HUMANBioGRID, IntAct25036637 26186194 details