Entity Details

Primary name ENPP7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6UWV6
EntryNameENPP7_HUMAN
FullNameEctonucleotide pyrophosphatase/phosphodiesterase family member 7
TaxID9606
Evidenceevidence at protein level
Length458
SequenceStatuscomplete
DateCreated2005-03-15
DateModified2021-06-02

Ontological Relatives

GenesENPP7

GO terms

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GOName
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005902 microvillus
GO:0006684 sphingomyelin metabolic process
GO:0006685 sphingomyelin catabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0008081 phosphoric diester hydrolase activity
GO:0008156 negative regulation of DNA replication
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0016020 membrane
GO:0044241 lipid digestion
GO:0045797 positive regulation of intestinal cholesterol absorption
GO:0055089 fatty acid homeostasis
GO:1904729 regulation of intestinal lipid absorption
GO:2000304 positive regulation of ceramide biosynthetic process
GO:2000755 positive regulation of sphingomyelin catabolic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferaseFamilyFamily
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR029895 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7FamilyFamily

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
ENPP7_HUMANGOGA2_HUMANBioGRID, IntAct32296183 details
ENPP7_HUMANMTUS2_HUMANBioGRID, IntAct32296183 details
ENPP7_HUMANBACH2_HUMANBioGRID, IntAct32296183 details
ENPP7_HUMANLRC73_HUMANBioGRID, IntAct32296183 details
ENPP7_HUMANKRA59_HUMANBioGRID, IntAct32296183 details