Entity Details

Primary name SETX_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z333
EntryNameSETX_HUMAN
FullNameProbable helicase senataxin
TaxID9606
Evidenceevidence at protein level
Length2677
SequenceStatuscomplete
DateCreated2004-06-07
DateModified2021-06-02

Ontological Relatives

GenesSETX

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000228 nuclear chromosome
GO:0000781 chromosome, telomeric region
GO:0001147 transcription termination site sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0006353 DNA-templated transcription, termination
GO:0006369 termination of RNA polymerase II transcription
GO:0006376 mRNA splice site selection
GO:0006396 RNA processing
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0007399 nervous system development
GO:0007623 circadian rhythm
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010976 positive regulation of neuron projection development
GO:0016604 nuclear body
GO:0030154 cell differentiation
GO:0030424 axon
GO:0030426 growth cone
GO:0033120 positive regulation of RNA splicing
GO:0034599 cellular response to oxidative stress
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043491 protein kinase B signaling
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045171 intercellular bridge
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060566 positive regulation of DNA-templated transcription, termination
GO:0070301 cellular response to hydrogen peroxide
GO:0071300 cellular response to retinoic acid
GO:2000144 positive regulation of DNA-templated transcription, initiation
GO:2000806 positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled

Subcellular Location

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Subcellular Location
Cell projection
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR041677 DNA2/NAM7 helicase, helicase domainDomainDomain
IPR041679 DNA2/NAM7 helicase-like, C-terminalDomainDomain

Diseases

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