Entity Details

Primary name CLAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z460
EntryNameCLAP1_HUMAN
FullNameCLIP-associating protein 1
TaxID9606
Evidenceevidence at protein level
Length1538
SequenceStatuscomplete
DateCreated2005-10-11
DateModified2021-06-02

Ontological Relatives

GenesCLASP1

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000226 microtubule cytoskeleton organization
GO:0000776 kinetochore
GO:0001578 microtubule bundle formation
GO:0002162 dystroglycan binding
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005828 kinetochore microtubule
GO:0005829 cytosol
GO:0005876 spindle microtubule
GO:0005881 cytoplasmic microtubule
GO:0005938 cell cortex
GO:0006903 vesicle targeting
GO:0007020 microtubule nucleation
GO:0007026 negative regulation of microtubule depolymerization
GO:0007030 Golgi organization
GO:0007052 mitotic spindle organization
GO:0007163 establishment or maintenance of cell polarity
GO:0008017 microtubule binding
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0010458 exit from mitosis
GO:0010470 regulation of gastrulation
GO:0010634 positive regulation of epithelial cell migration
GO:0010717 regulation of epithelial to mesenchymal transition
GO:0016020 membrane
GO:0030953 astral microtubule organization
GO:0030981 cortical microtubule cytoskeleton
GO:0031023 microtubule organizing center organization
GO:0031111 negative regulation of microtubule polymerization or depolymerization
GO:0031116 positive regulation of microtubule polymerization
GO:0031592 centrosomal corona
GO:0034453 microtubule anchoring
GO:0035371 microtubule plus-end
GO:0040001 establishment of mitotic spindle localization
GO:0043515 kinetochore binding
GO:0045180 basal cortex
GO:0045921 positive regulation of exocytosis
GO:0051010 microtubule plus-end binding
GO:0051294 establishment of spindle orientation
GO:0051301 cell division
GO:0051497 negative regulation of stress fiber assembly
GO:0051893 regulation of focal adhesion assembly
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0072686 mitotic spindle
GO:0090091 positive regulation of extracellular matrix disassembly
GO:0090162 establishment of epithelial cell polarity
GO:0090307 mitotic spindle assembly
GO:0097711 ciliary basal body-plasma membrane docking
GO:1903690 negative regulation of wound healing, spreading of epidermal cells
GO:1904261 positive regulation of basement membrane assembly involved in embryonic body morphogenesis

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR021133 HEAT, type 2RepeatRepeat
IPR024395 CLASP N-terminal domainDomainDomain
IPR028399 CLIP-associating protein 1FamilyFamily
IPR034085 TOG domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule