Entity Details

Primary name SMS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86VZ5
EntryNameSMS1_HUMAN
FullNamePhosphatidylcholine:ceramide cholinephosphotransferase 1
TaxID9606
Evidenceevidence at protein level
Length413
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesSGMS1

GO terms

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GOName
GO:0000138 Golgi trans cisterna
GO:0000139 Golgi membrane
GO:0002950 ceramide phosphoethanolamine synthase activity
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006686 sphingomyelin biosynthetic process
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0016301 kinase activity
GO:0030148 sphingolipid biosynthetic process
GO:0030173 integral component of Golgi membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0033188 sphingomyelin synthase activity
GO:0046513 ceramide biosynthetic process
GO:0047493 ceramide cholinephosphotransferase activity
GO:0071222 cellular response to lipopolysaccharide
GO:0071356 cellular response to tumor necrosis factor
GO:2001242 regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR001660 Sterile alpha motif domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR025749 Sphingomyelin synthase-like domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SMS1_HUMANATX1_HUMANBioGRID, HPRD, IntAct16713569 details
SMS1_HUMANSTK4_HUMANBioGRID22863277 details