Entity Details

Primary name SIX5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N196
EntryNameSIX5_HUMAN
FullNameHomeobox protein SIX5
TaxID9606
Evidenceevidence at protein level
Length739
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesSIX5

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002088 lens development in camera-type eye
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007286 spermatid development
GO:0045892 negative regulation of transcription, DNA-templated
GO:1902723 negative regulation of skeletal muscle satellite cell proliferation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR031701 Homeobox protein SIX1, N-terminal SD domainDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SIX5_HUMANATX1_HUMANBioGRID, HPRD, IntAct16713569 details
SIX5_HUMANEYA3_HUMANBioGRID, HPRD10490620 details
SIX5_HUMANHMGB1_HUMANHPRD11748221 details