Entity Details

Primary name SC5A8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N695
EntryNameSC5A8_HUMAN
FullNameSodium-coupled monocarboxylate transporter 1
TaxID9606
Evidenceevidence at protein level
Length610
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesSLC5A8

GO terms

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GOName
GO:0005343 organic acid:sodium symporter activity
GO:0005886 plasma membrane
GO:0006811 ion transport
GO:0006814 sodium ion transport
GO:0006915 apoptotic process
GO:0015129 lactate transmembrane transporter activity
GO:0015293 symporter activity
GO:0015552 propionate transmembrane transporter activity
GO:0015730 propanoate transport
GO:0015913 short-chain fatty acid import
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway
GO:0070062 extracellular exosome
GO:0140161 monocarboxylate:sodium symporter activity

Subcellular Location

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Subcellular Location
Apical cell membrane

Domains

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DomainNameCategoryType
IPR001734 Sodium/solute symporterFamilyFamily
IPR038377 Sodium/glucose symporter superfamilyFamilyHomologous superfamily
IPR041992 SMCT1, solute-binding domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00121 BiotinDrugbanksmall molecule
DB00627 NiacinDrugbanksmall molecule
DB01762 Acetoacetic acidDrugbanksmall molecule
DB08872 Gabapentin enacarbilDrugbanksmall molecule
DB08949 Inositol nicotinateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SC5A8_HUMANPZRN3_HUMANBioGRID31098988 details