Entity Details

Primary name SYT8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NBV8
EntryNameSYT8_HUMAN
FullNameSynaptotagmin-8
TaxID9606
Evidenceevidence at transcript level
Length401
SequenceStatuscomplete
DateCreated2003-11-28
DateModified2021-06-02

Ontological Relatives

GenesSYT8

GO terms

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GOName
GO:0000149 SNARE binding
GO:0001669 acrosomal vesicle
GO:0001786 phosphatidylserine binding
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
GO:0005886 plasma membrane
GO:0007340 acrosome reaction
GO:0014059 regulation of dopamine secretion
GO:0016021 integral component of membrane
GO:0016192 vesicle-mediated transport
GO:0017156 calcium-ion regulated exocytosis
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0019905 syntaxin binding
GO:0030276 clathrin binding
GO:0030424 axon
GO:0030672 synaptic vesicle membrane
GO:0031045 dense core granule
GO:0048306 calcium-dependent protein binding
GO:0048488 synaptic vesicle endocytosis
GO:0048791 calcium ion-regulated exocytosis of neurotransmitter
GO:0070382 exocytic vesicle
GO:0071277 cellular response to calcium ion

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR001565 SynaptotagminDomainDomain
IPR030540 Synaptotagmin-8FamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SYT8_HUMANHNRPQ_HUMANBioGRID, HPRD10734137 details