Entity Details

Primary name NOXO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NFA2
EntryNameNOXO1_HUMAN
FullNameNADPH oxidase organizer 1
TaxID9606
Evidenceevidence at protein level
Length376
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesNOXO1

GO terms

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GOName
GO:0005543 phospholipid binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006801 superoxide metabolic process
GO:0010310 regulation of hydrogen peroxide metabolic process
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0019899 enzyme binding
GO:0022617 extracellular matrix disassembly
GO:0031343 positive regulation of cell killing
GO:0035091 phosphatidylinositol binding
GO:0043020 NADPH oxidase complex
GO:0060090 molecular adaptor activity
GO:0060263 regulation of respiratory burst

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001683 Phox homologyDomainDomain
IPR035758 NADPH oxidase organiser 1, second SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036871 PX domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB05265 EcabetDrugbanksmall molecule