Entity Details

Primary name SOX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00570
EntryNameSOX1_HUMAN
FullNameTranscription factor SOX-1
TaxID9606
Evidenceevidence at protein level
Length391
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSOX1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002089 lens morphogenesis in camera-type eye
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
GO:0021521 ventral spinal cord interneuron specification
GO:0021884 forebrain neuron development
GO:0030154 cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048713 regulation of oligodendrocyte differentiation
GO:1904936 interneuron migration
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR022097 Transcription factor SOXFamilyFamily
IPR031268 Transcription factor SOX-1FamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SOX1_HUMANSTAT3_HUMANMolecular Connections20929579 details
SOX1_HUMANCTNB1_HUMANBioGRID, HPRD15110721 22767186 details