Entity Details

Primary name DLG5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TDM6
EntryNameDLG5_HUMAN
FullNameDisks large homolog 5
TaxID9606
Evidenceevidence at protein level
Length1919
SequenceStatuscomplete
DateCreated2003-01-10
DateModified2021-06-02

Ontological Relatives

GenesDLG5

GO terms

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GOName
GO:0001837 epithelial to mesenchymal transition
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0007165 signal transduction
GO:0008013 beta-catenin binding
GO:0008092 cytoskeletal protein binding
GO:0008285 negative regulation of cell population proliferation
GO:0014069 postsynaptic density
GO:0030011 maintenance of cell polarity
GO:0030054 cell junction
GO:0030159 signaling receptor complex adaptor activity
GO:0030336 negative regulation of cell migration
GO:0030859 polarized epithelial cell differentiation
GO:0030901 midbrain development
GO:0035331 negative regulation of hippo signaling
GO:0035332 positive regulation of hippo signaling
GO:0035556 intracellular signal transduction
GO:0036064 ciliary basal body
GO:0042130 negative regulation of T cell proliferation
GO:0042981 regulation of apoptotic process
GO:0045176 apical protein localization
GO:0045186 zonula adherens assembly
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0045880 positive regulation of smoothened signaling pathway
GO:0051965 positive regulation of synapse assembly
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060999 positive regulation of dendritic spine development
GO:0065003 protein-containing complex assembly
GO:0071896 protein localization to adherens junction
GO:0072205 metanephric collecting duct development
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR001315 CARD domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR006907 Domain of unknown function DUF622DomainDomain
IPR008144 Guanylate kinase-like domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035537 Disks large homologue 5, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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