Entity Details

Primary name ES8L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TE68
EntryNameES8L1_HUMAN
FullNameEpidermal growth factor receptor kinase substrate 8-like protein 1
TaxID9606
Evidenceevidence at protein level
Length723
SequenceStatuscomplete
DateCreated2006-05-30
DateModified2021-06-02

Ontological Relatives

GenesEPS8L1

GO terms

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GOName
GO:0003779 actin binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007266 Rho protein signal transduction
GO:0032587 ruffle membrane
GO:0032991 protein-containing complex
GO:0035023 regulation of Rho protein signal transduction
GO:0042608 T cell receptor binding
GO:0045296 cadherin binding
GO:0050790 regulation of catalytic activity
GO:0070062 extracellular exosome
GO:1900029 positive regulation of ruffle assembly

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR013625 Tensin/EPS8 phosphotyrosine-binding domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR033928 Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domainDomainDomain
IPR035462 Eps8, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR039801 Epidermal growth factor receptor kinase substrate 8-likeFamilyFamily
IPR041418 SAM domainDomainDomain

Diseases

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