Entity Details

Primary name HMHA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92619
EntryNameHMHA1_HUMAN
FullNameRho GTPase-activating protein 45
TaxID9606
Evidenceevidence at protein level
Length1136
SequenceStatuscomplete
DateCreated2008-04-29
DateModified2021-06-02

Ontological Relatives

GenesARHGAP45

GO terms

Show/Hide Table
GOName
GO:0005096 GTPase activator activity
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0016020 membrane
GO:0032587 ruffle membrane
GO:0034774 secretory granule lumen
GO:0035556 intracellular signal transduction
GO:0035578 azurophil granule lumen
GO:0043312 neutrophil degranulation
GO:0046872 metal ion binding
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0090630 activation of GTPase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cell projection
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001060 FCH domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR031160 F-BAR domainDomainDomain

Diseases

Show/Hide Table