Entity Details

Primary name ITBP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14713
EntryNameITBP1_HUMAN
FullNameIntegrin beta-1-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length200
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesITGB1BP1

GO terms

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GOName
GO:0001726 ruffle
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0005092 GDP-dissociation inhibitor activity
GO:0005178 integrin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006469 negative regulation of protein kinase activity
GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0007160 cell-matrix adhesion
GO:0007219 Notch signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0010595 positive regulation of endothelial cell migration
GO:0010764 negative regulation of fibroblast migration
GO:0016020 membrane
GO:0016477 cell migration
GO:0016604 nuclear body
GO:0030027 lamellipodium
GO:0030154 cell differentiation
GO:0031214 biomineral tissue development
GO:0032091 negative regulation of protein binding
GO:0032148 activation of protein kinase B activity
GO:0033622 integrin activation
GO:0033628 regulation of cell adhesion mediated by integrin
GO:0034451 centriolar satellite
GO:0035148 tube formation
GO:0035556 intracellular signal transduction
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0043087 regulation of GTPase activity
GO:0043113 receptor clustering
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045747 positive regulation of Notch signaling pathway
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048471 perinuclear region of cytoplasm
GO:0051451 myoblast migration
GO:0051496 positive regulation of stress fiber assembly
GO:0051781 positive regulation of cell division
GO:0051895 negative regulation of focal adhesion assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071944 cell periphery
GO:0072659 protein localization to plasma membrane
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis
GO:0090314 positive regulation of protein targeting to membrane
GO:0090315 negative regulation of protein targeting to membrane
GO:0097746 blood vessel diameter maintenance
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:2001044 regulation of integrin-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR019517 Integrin binding protein, ICAP-1FamilyFamily

Diseases

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